Related Experiment Video
Updated: Sep 25, 2025

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−
Published on: July 27, 2018
Negative ion formation and fragmentation upon dissociative electron attachment to the nicotinamide molecule
Patrick Ziegler1, Andrzej Pelc2, Eugene Arthur-Baidoo1
1Institute for Ion Physics and Applied Physics, University of Innsbruck Technikerstrasse 25 6020 Innsbruck Austria Milan.Oncak@uibk.ac.at Stephan.Denifl@uibk.ac.at.
None:
Nicotinamide (C6H6N2O) is a biologically relevant molecule. This compound has several important roles related to the anabolic and metabolic processes that take place in living organisms. It is also used as a radiosensitizer in tumor therapy. As a result of the interaction of high-energy radiation with matter, low-energy electrons are also released, which can also interact with other molecules, forming several types of ions. In the present investigation, dissociative electron attachment to C6H6N2O has been studied in a crossed electron-molecular beams experiment in the electron energy range of about 0-15 eV. In the experiment, six anionic species were detected: C6H5N2O-, C5H4N-, NCO-, O-/NH2 -, and CN-, with NCO- being the most prominent anion. We also provide detailed computational results regarding the energetic thresholds and pathways of the respective dissociative electron attachment (DEA) channels. The experimental results are compared with the theoretical ones and on this basis, the possible DEA reactions for the formation of anions at a given resonance energy were assigned as well as the generation of neutrals fragments such as pyridine and its several derivatives and radicals are predicted. The pyridine ring seems to stay intact during the DEA process.
More Related Videos
Related Concept Videos
Mass Spectrometry: Molecular Fragmentation Overview
One type of fragmentation pattern is the cleavage of a single bond in the molecular ion. The cleavage leads to a radical and a cation. The cleavage can...
Role of Reduced Coenzymes NADH and FADH₂
Oxidation and Reduction of Organic Molecules
The removal of an electron from a molecule, results in a...
Electron Carriers
Over the many stages of cellular respiration, glucose breaks down into carbon dioxide and water. Electron carriers pick up electrons lost by glucose in these reactions, temporarily storing and releasing them into the electron...
2° Amines to N-Nitrosamines: Reaction with NaNO2
Mass Spectrometry: Carboxylic Acid, Ester, and Amide Fragmentation
For example,...

