Related Experiment Video
Updated: Sep 24, 2025

05:39
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
236
Laugier-Hunziker syndrome: a case and dermoscopic features.
Vito Ingordo1, Gerardo Ferrara, Grazia Marangi
1Outpatient Department of Dermatology, Local Health Centre Taranto, Taranto, Italy,. vito.ingordo@gmail.com.
Dermatology Online Journal
|May 2, 2022
Summary
Laugier-Hunziker syndrome (LHS) is a rare condition causing brown spots on lips, mouth, and skin. This case highlights the need for more dermoscopic observations to improve future diagnoses of this acquired disorder.
Area of Science:
- Dermatology
- Medical Case Reports
Background:
- Laugier-Hunziker syndrome (LHS) is an infrequent, acquired condition.
- It presents with characteristic brown macules on the lips, oral mucosa, and acral skin.
- Melanonychia of nails can coexist, with no other systemic involvement.
Observation:
- A case of LHS in a 50-year-old woman is detailed.
- Particular attention is given to the dermoscopic features observed in this patient.
- Current literature lacks specific dermoscopic findings for LHS mucosal/cutaneous maculae.
Findings:
- The case contributes to the limited body of knowledge on LHS.
- Dermoscopic examination was performed on the pigmented lesions.
- No pathognomonic dermoscopic features for LHS maculae are established.
Implications:
- Further accumulation of dermoscopic observations in LHS cases is crucial.
- Distinct dermoscopic findings could enhance diagnostic accuracy for LHS.
- This research underscores the importance of detailed case reporting in rare dermatological conditions.
Related Concept Videos
Skin Cancer
4.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.7K
Papillary Dermis
3.8K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
3.8K
Skin Diseases and Disorders
4.3K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.3K
Desmosomes
5.8K
The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
5.8K
Changes in Skin Color: Clinical Perspectives
2.4K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.4K

