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Fulminant fungal endogenous endophthalmitis following SARS-CoV-2 infection: A case report
Mukesh Jain1, Anand Singh Brar1, Suryasnata Rath2
1Anant Bajaj Retina Institute, L.V. Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.
Abstract:
Systemic corticosteroids and immunocompromised state following SARS-CoV-2 infection can predispose individuals to endogenous endophthalmitis. A 66-year-old gentleman presented with complaints of diminution of vision and redness one week post discharge after hospitalization for COVID-19 infection. Clinical examination suggested fulminant endogenous endophthalmitis which responded poorly even after aggressive treatment requiring evisceration. Culture and gene sequenced analysis confirmed Aspergillus fumigatus to be the causative organism. A high degree of suspicion is warranted in the presence of recent onset of floaters in COVID-19-infected individuals to facilitate early diagnosis and outcomes.
Insights
COVID-19 survivors are at risk for endogenous endophthalmitis, a severe eye infection. Early detection of vision loss and eye redness in these patients is crucial for better outcomes.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Systemic corticosteroids and SARS-CoV-2 infection can lead to immunocompromised states.
- These conditions increase the risk of endogenous endophthalmitis.
Observation:
- A 66-year-old male presented with vision loss and redness post-COVID-19 hospitalization.
- Clinical examination revealed fulminant endogenous endophthalmitis.
Findings:
- The patient's condition required evisceration despite aggressive treatment.
- Aspergillus fumigatus was identified as the causative organism via culture and gene sequencing.
Implications:
- A high index of suspicion for endogenous endophthalmitis is necessary in COVID-19 patients with new floaters.
- Prompt diagnosis and treatment are vital for improving visual outcomes in at-risk individuals.
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