Related Experiment Video
Updated: Sep 24, 2025
06:39
Biological Preparation and Mechanical Technique for Determining Viscoelastic Properties of Zonular Fibers
Published on: December 16, 2021
2.2K
Myopia in the Diagnosis of Marfan Syndrome: An Important Early Sign of a Systemic Condition
Bhavini B Prajapati1, Jennifer Monti2
1Internal Medicine - Pediatrics, Maine Medical Center, Portland, USA.
Cureus
|May 4, 2022
Abstract:
Marfan syndrome is a genetic connective tissue disorder that is a frequent cause of aortic dissection in younger patients. We report a case of a patient with a history of ectopia lentis in his third decade and abdominal striae since adolescence, who presented with Stanford type A dissection at age 48.
Insights
Marfan syndrome, a genetic disorder, can lead to aortic dissection. This case highlights a 48-year-old patient with Marfan syndrome presenting with a Stanford type A dissection.
Area of Science:
- Cardiology
- Genetics
- Connective Tissue Diseases
Background:
- Marfan syndrome is an inherited disorder affecting connective tissue.
- It is a known risk factor for aortic dissection, particularly in younger individuals.
Observation:
- A 48-year-old male presented with Stanford type A aortic dissection.
- He had a history of ectopia lentis (lens dislocation) diagnosed in his thirties.
- Abdominal striae were noted since adolescence.
Findings:
- The patient's clinical presentation and history are consistent with Marfan syndrome.
- The case illustrates a later-onset presentation of aortic dissection in a Marfan syndrome patient.
Implications:
- This case underscores the importance of recognizing Marfan syndrome in patients with aortic dissection, regardless of age.
- Early diagnosis and management of Marfan syndrome can help prevent life-threatening cardiovascular events like aortic dissection.
Related Concept Videos
01:30Aneurysm I: Introduction
34
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
34
01:25Glaucoma: Overview
860
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
860
01:27Mitral Valve Prolapse I: Introduction
55
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
55
01:22Mitral Stenosis I: Introduction
60
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
60
01:22Photoreceptors and Visual Pathways
6.6K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.6K
01:16Focusing of Light in the Eye
3.3K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.3K