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Pancreatic liposarcoma: a case report.

Masahiro Tanabe1, Hiroto Matsui2, Mayumi Higashi3

  • 1Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. m-tanabe@yamaguchi-u.ac.jp.

Abdominal Radiology (New York)
|May 4, 2022
PubMed
Summary

A rare pancreatic liposarcoma was diagnosed in an 81-year-old woman 12 years after thyroid cancer surgery. Computed tomography (CT) tracked the tumor

Keywords:
Computed tomographyDistal pancreatectomy and splenectomyLiposarcomaPancreas

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Area of Science:

  • Oncology
  • Radiology
  • Surgical Pathology

Background:

  • A patient with a history of papillary thyroid cancer and metastases developed a pancreatic tumor.
  • The pancreas is an exceptionally rare site for primary liposarcoma.

Observation:

  • Computed tomography (CT) revealed a 26 mm pancreatic tail mass with initial fat components.
  • The pancreatic tumor grew over time, while lung metastases remained stable.
  • Imaging showed heterogeneous tumor characteristics with evolving fat component visibility on CT.

Findings:

  • Surgical resection confirmed a dedifferentiated liposarcoma with a well-differentiated component.
  • The pancreatic liposarcoma appeared during follow-up for a prior thyroid malignancy.

Implications:

  • This case highlights the possibility of rare pancreatic tumors in patients with a history of other cancers.
  • Serial CT imaging is valuable for monitoring tumor evolution and characteristics.
  • Pancreatic liposarcoma, though rare, should be considered in the differential diagnosis of pancreatic masses.