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Published on: December 1, 2020
Xenobots: Applications in Drug Discovery.
Nilay Solanki1, Sagar Mahant1, Swayamprakash Patel2
1Department of Pharmacology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Gujarat, India.
Living xenobots, built from frog cells and AI, show promise in drug discovery and treating diseases like Alzheimer's and cancer. Their unique design and self-repairing abilities offer new therapeutic possibilities.
Area of Science:
- Biotechnology
- Artificial Intelligence
- Robotics
Background:
- Xenobots represent a novel class of living robots constructed from frog embryonic stem cells.
- Their creation merges expertise from biosciences, artificial intelligence, and computer science.
Approach:
- Designs are generated using artificial intelligence in in vitro and in silico models.
- Software analyzes and filters designs, with in vivo development in MMR solution replicating the selected forms.
- Xenobots are evaluated based on their behavior, movement, function, and inherent features.
Key Points:
- Xenobots are utilized in medical and pharmaceutical research for evaluating new drug delivery systems.
- Their self-repairing properties enable targeted drug delivery and reduced cytotoxicity in cancer treatment.
- Potential applications include treating neurodegenerative diseases like Alzheimer's and Parkinson's.
Conclusions:
- Xenobots offer a groundbreaking platform for drug discovery and targeted therapies.
- Future research aims to leverage xenobots for treating chronic illnesses and their complications.
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