Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Secondary Lymphoid Organs

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...

Autoimmune Disorders

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Reticular Dermis

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...

Primary Lymphoid Organs

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Variations in Healthcare Provider Interactions and Treatment Satisfaction by Patient Race and Ethnicity: A Survey of Adults with Atopic Dermatitis.

Advances in therapy·2026

Same author

Early Infantile Hemangioma Diagnosis Is Key in Skin of Color.

Cutis·2026

Same author

Pseudofolliculitis Barbae in the Military: Policy, Stigma, and Practical Solutions.

Cutis·2025

Same author

Don't Miss These Signs of Rosacea in Darker Skin Types.

Cutis·2025

Same author

Beyond Fitzpatrick skin types: A Delphi consensus on key considerations for a universal skin typing classification.

Journal of the American Academy of Dermatology·2025

Same author

Consider Cultural Practices and Barriers to Care When Treating Alopecia Areata.

Cutis·2025

Search research articles

Related Experiment Video

Updated: Sep 24, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Discoid lupus.

Candrice R Heath¹, Richard P Usatine²

¹Department of Dermatology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.

The Journal of Family Practice

|May 4, 2022

Summary

This summary is machine-generated.

This study compares facial skin lesions in two women, highlighting differences in plaque color and presentation based on skin tone. It emphasizes how dermatological conditions manifest uniquely across diverse complexions.

More Related Videos

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

Related Experiment Videos

Last Updated: Sep 24, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

Area of Science:

Dermatology
Clinical Medicine
Medical Imaging

Background:

Facial dermatoses present with varied clinical manifestations.
Understanding variations in skin lesion appearance is crucial for accurate diagnosis.

Observation:

Case 1: A 30-year-old woman with darker skin tone presented with multicolored (pink, brown, white) indurated plaques in a butterfly distribution on her face.
Case 2: A 19-year-old woman with lighter skin tone exhibited pink, elevated, indurated plaques with hypopigmentation, also in a butterfly distribution on her face.

Findings:

The study observed distinct morphological differences in facial plaques between individuals with darker and lighter skin tones.
Lesion coloration and hypopigmentation patterns varied significantly, suggesting an influence of melanin content on the presentation of these dermatoses.

Implications:

These findings underscore the importance of considering skin tone in the dermatological assessment of facial conditions.
Recognizing these variations can improve diagnostic accuracy and guide appropriate treatment strategies for a diverse patient population.