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Drugs for Treatment of Constipation-Predominant IBS

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...

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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

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Published on: July 5, 2024

Complete Currarino Triad Presenting With Chronic Constipation.

Habib Y Aldabbab¹, Hussain A Al Ghadeer², Ashraf A Alnosair³

¹Orthopedic Surgery, King Faisal University, AlAhsa, SAU.

|May 5, 2022

Summary

Currarino syndrome, a congenital disorder, presents with anorectal malformation, sacrococcygeal anomalies, and a presacral mass. Early diagnosis via MRI and surgical intervention are key for managing this autosomal dominant condition.

Keywords:

anorectal malformation chronic constipation currarino syndrome sacral defect saudi arabia

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Area of Science:

Pediatric Surgery
Medical Imaging
Genetics

Background:

Currarino syndrome (CS) is a rare autosomal dominant congenital disorder.
It is defined by a characteristic triad: anorectal malformation, sacrococcygeal anomalies, and a presacral mass.
Chronic constipation is the most frequent clinical manifestation.

Observation:

An eight-month-old female infant presented with persistent chronic constipation.
Physical examination revealed abdominal distension and anal stenosis.
Radiographic imaging, including MRI, identified sacrococcygeal abnormalities and a presacral mass.

Findings:

The diagnostic findings confirmed Currarino syndrome in the infant.
Magnetic Resonance Imaging (MRI) demonstrated high sensitivity in diagnosing the condition.
Surgical management involved the excision of the presacral mass and anorectoplasty.

Implications:

This case highlights the importance of recognizing the clinical triad of Currarino syndrome.
MRI is crucial for accurate diagnosis of CS.
Surgical intervention, including mass excision and anorectoplasty, is effective for managing CS patients.