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Doxycycline-Associated Hyperpigmentation: A Case Report and Literature Review
Antara Afrin1, Philip R Cohen2
1Dermatology, Michigan State University College of Human Medicine, East Lansing, USA.
Cureus
|May 5, 2022
Summary
Drug-induced hyperpigmentation from doxycycline is uncommon but reversible. Discontinuing the medication led to significant skin pigmentation improvement in a patient and in most literature cases.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Drug-induced hyperpigmentation is a known adverse cutaneous effect of systemic medications.
- Doxycycline, a common antibiotic, has been rarely associated with this side effect.

