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Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples
Keisuke Oshimi1,2, Yushi Nishimura2,3, Tsutomu Matsubara4
1Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan. masazumi@okayama-u.ac.jp.
Lab on a Chip
|May 5, 2022
Summary
We developed a chip-based antenna for detecting optically detected magnetic resonance (ODMR) in nanodiamonds. This innovation enables scalable quantum sensing for various bioassays.
Area of Science:
- Quantum Sensing
- Microwave Engineering
- Nanotechnology
Background:
- Optically Detected Magnetic Resonance (ODMR) is a powerful technique for probing spin properties.
- Current ODMR setups often lack scalability and on-chip integration for biological applications.
Purpose of the Study:
- To design and demonstrate a chip-based microwave antenna for on-chip ODMR detection.
- To enable scalable integration of ODMR quantum sensing into bioassay platforms.
Main Methods:
- Fabrication of a notch-shaped coplanar waveguide antenna on a glass substrate using lithography.
- Characterization of the antenna's detection area, broadband characteristics, and reflection.
- Demonstration of uniform ODMR signal detection across various biological samples.
Main Results:
- A millimeter-scale (1.5 × 2.0 mm²) ODMR detection area with gigahertz-broadband characteristics and low reflection (<8%).
- Quantitative predictability of ODMR signal intensity via numerical simulation.
- Uniform ODMR signal detection demonstrated for cells, tissue, and worms.
Conclusions:
- The chip-based microwave antenna facilitates on-chip ODMR detection of fluorescent nanodiamonds.
- This architecture enables scalable integration of ODMR quantum sensing into diverse bioassay platforms.

