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Related Concept Videos

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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Updated: Sep 24, 2025

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
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X-ray zooming optics for analyzer-based multi-contrast computed tomography.

Keiichi Hirano1, Hiroshi Sugiyama1, Ryutaro Nishimura1

  • 1Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization, 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan.

Journal of Synchrotron Radiation
|May 5, 2022
PubMed
Summary

A novel X-ray analyzer optics with zoom capability offers enhanced imaging for diverse samples. This advanced system provides superior image quality at higher magnifications, benefiting various scientific fields.

Keywords:
X-ray Bragg magnifieranalyzer-based imagingcomputed tomography

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Area of Science:

  • Materials Science
  • Condensed Matter Physics
  • Biomedical Science
  • Archeology

Background:

  • Traditional X-ray imaging techniques have limitations in resolving fine details and contrasting diverse sample types.
  • The need for adaptable X-ray optics capable of high-resolution imaging across multiple contrast modes is critical for scientific advancement.

Purpose of the Study:

  • To propose and demonstrate an X-ray analyzer-based optics system with an integrated zoom function.
  • To enable multi-modal contrast imaging (absorption, phase, scattering) with variable magnification for detailed sample analysis.

Main Methods:

  • Development of a non-dispersive (+,-) X-ray optics system using collimator and analyzer crystals.
  • Implementation of a zoom function via an asymmetrically cut crystal in a rotated-inclined geometry for the analyzer.
  • Proof-of-principle experiments conducted at the Photon Factory's BL-14B beamline, utilizing computed tomography for image acquisition.

Main Results:

  • Successful demonstration of tri-modal contrast imaging with magnifications of 1× and 10×.
  • Quantitative confirmation that image quality at 10× magnification is significantly superior to that at 1×.
  • Validation of the zoom optics' capability to observe entire samples or specific regions of interest.

Conclusions:

  • The developed X-ray analyzer optics with a zoom function provides a powerful new tool for high-resolution imaging.
  • This technology enhances the ability to study samples across various scientific disciplines by offering optimal magnification and multi-modal contrast.
  • The system is poised to make significant contributions to materials science, physics, archeology, and biomedical research.