Related Experiment Video
Updated: Sep 24, 2025

Towards Biomimicking Wood: Fabricated Free-standing Films of Nanocellulose, Lignin, and a Synthetic Polycation
Published on: June 17, 2014
Dissolution performance of cellulose in [A2im][MOA]/MIM solvents
Airong Xu1, Yongxin Wang1, Changzhu Li2,3
1School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology Luoyang Henan 471003 PR China airongxu@haust.edu.cn +86-379-64231914 +86-379-64231914.
Abstract:
Cellulose solvents ([A2im][MOA]/MIM) were developed by combining diallylimidazolium methoxyacetate ([A2im][MOA]) with N-methylimidazole (MIM). The cellulose solubilities in the ([A2im][MOA]/MIM) solvents were determined at 25 °C, and the effect of the MIM/[A2im][MOA] molar ratio on cellulose solubility was systematically investigated. Attractively, the solvents show cellulose solubility as high as 25.2 g 100 g-1 even at 25 °C. It is proposed that the H2, H4 and H6 in [A2im]+ and the carboxyl O atom in [MOA]- primarily contribute to the dissolution of cellulose; MIM mainly acts to dissociate [A2im][MOA] into [A2im]+ and [MOA]-, and stabilize the dissolved cellulose chains. Moreover, the porous cellulose materials with varying morphological structures could be tailored by simply tuning the cellulose solution concentration, and the formation mechanism of the cellulose material was discussed.
Related Concept Videos
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Factors Affecting Dissolution: Drug pKa, Lipophilicity and GI pH
A drug's pKa and the pH of the gastrointestinal (GI) tract play crucial roles...
Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism
Some polymorphic crystals possess lower aqueous solubility than their amorphous counterparts, leading to incomplete absorption. For instance, the oral suspension of Chloramphenicol, which...
Theories of Dissolution: Diffusion Layer Model
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...
Intermolecular Forces in Solutions
When the strengths of the intermolecular forces of attraction between solute and solvent species in a solution are no different than those present in the separated components, the solution is formed with no accompanying energy change. Such a solution is called an ideal solution. A mixture of ideal gases (or gases such as helium and argon,...
Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

