Crescendo Angina Secondary to Congenital Absence of the Left Circumflex Coronary Artery: A Case Report
Esiemoghie J Akhigbe1, Ebubechukwu Ezeh1, Mohammad Amro2
1Internal Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Insights
Congenital coronary artery anomalies, like absent left circumflex artery (LCx), are rare. Their combination with atherosclerosis can cause serious heart problems, highlighting the need for careful diagnosis and management.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Vascular Anatomy
Background:
- Congenital coronary artery abnormalities (CAAs) are rare cardiovascular malformations.
- The left circumflex artery (LCx) anomaly is the most frequent type of CAA.
- While often asymptomatic, CAAs can manifest as angina-like symptoms in a subset of patients.
Observation:
- A 71-year-old male presented with crescendo angina and a positive chemical stress test.
- Coronary angiography revealed an absent left circumflex artery (LCx) and a superdominant right coronary artery (RCA).
Findings:
- Congenital absence of the LCx is typically a benign finding.
- The coexistence of LCx anomaly with significant atherosclerotic coronary artery disease poses a risk for substantial morbidity and mortality.
Implications:
- Understanding the embryological and morphological basis of CAAs is crucial for accurate diagnosis.
- Effective management strategies for patients with coexisting CAAs and atherosclerosis are essential.
- This case underscores the importance of considering anatomical variations in the diagnosis of ischemic heart disease.
Abstract:
Congenital coronary artery abnormalities (CAAs) are very rare in the general population. Among these congenital anomalies, left circumflex artery (LCx) anomaly is the most common. Although many are asymptomatic, a small percentage of patients with this anomaly present with angina-like symptoms. Usually, a majority of these cases are found incidentally during coronary angiography. We present a 71-year-old male with crescendo angina with a positive chemical stress test. Coronary angiography showed an absent LCx and a superdominant right coronary artery (RCA). Although congenital LCx absence is a benign finding, the coexistence of this abnormality with significant atherosclerotic disease in the coronary artery can lead to significant morbidity and mortality in this population. Understanding the embryological and morphological significance of these anomalies is important in adequately diagnosing and managing these patients.
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