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Praseodymium promotes B-Z transition in self-assembled DNA nanostructures
Madhabi M Bhanjadeo1,2, Umakanta Subudhi1,2
1DNA Nanotechnology & Application Laboratory, CSIR-Institute of Minerals & Materials Technology Bhubaneswar 751 013 India usubudhi@immt.res.in subudhisai@gmail.com.
RSC Advances
|May 6, 2022
Abstract:
Millimolar concentrations of PrCl3 can induce sequence-specific B-Z transition in various-self-assembled branched DNA (bDNA) nanostructures. Competitive dye binding and thermal kinetics suggest that the phosphate backbone and grooves of bDNA are wrapped with Pr3+ for stabilizing the Z-bDNA. Application of EDTA can convert Z-DNA back to the B-form.

