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Updated: Sep 24, 2025
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Rapid, Enzymatic Methods for Amplification of Minimal, Linear Templates for Protein Prototyping using Cell-Free Systems
Published on: June 14, 2021
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One step DNA amplification of mammalian cells in picoliter microwell arrays
Wenwen Liu1, Zhao Li1, Yuanjie Liu1
1State Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
RSC Advances
|May 6, 2022
Abstract:
We developed a strategy for direct DNA amplification of single cells on a PEG-modified silica chip with 30 600 picoliter-sized microwells. HPV-positive cells in heterogeneous populations were successfully detected with high accuracy sensitivity as high as single copy.
