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Single crystal X-ray structurally characterized dual functioning oxovanadium(iv) complex of amide-imine derivative:
Prasenjit Mandal1, Sangita Maji1, Shuli Barik2
1Department of Chemistry, The University of Burdwan Burdwan 713104 W.B. India ddas100in@yahoo.com +91-342-2530452 +91-342-2533913 (ext. 424).
Abstract:
An amide based imine derivative, 4-hydroxy-benzoic acid (phenyl(pyridine-2-yl)methanone-hydrazide) (PHP) forms a µ-oxo-bridged dinuclear oxovanadium(iv) complex (PHPV), the structure of which is authenticated by single crystal XRD analysis. The antidiabetic potential of PHPV has been established upon its oral treatment on mice, suffering from streptozotocin-induced diabetes. On the other hand, PHPV is also useful for selective fluorescence detection of thorium (Th4+) via a metal-ion displacement protocol where Th4+ displaces V(iv) from PHPV as established by spectroscopic studies. The lowest detection limit (LOD) of Th4+ is 12.27 nM while the displacement binding constant for Th4+ is 6.7 × 104 M-1.
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