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Updated: Sep 24, 2025

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach
Published on: December 4, 2021
Performance and selectivity of lower-rim substituted calix[4]arene as a stationary phase for capillary gas
Tao Sun1, Bin Li2, Xiaomin Shuai3
1College of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University Luoyang 471934 P. R. China suntao2226@163.com.
Abstract:
This work presents the investigation of p-tert-butyl(tetradecyloxy)calix[4]arene (C4A-C10) as stationary phase for capillary gas chromatographic (GC) separations. The statically-coated C4A-C10 capillary column showed weak polarity and column efficiency of 2566 plates per m determined by n-dodecane at 120 °C. Impressively, the C4A-C10 column exhibited extremely high resolving capability for a wide range of analytes from nonpolar to polar, including n-alkanes, esters, ketones, aldehydes, alcohols and bromoalkanes. Most importantly, the C4A-C10 column exhibited an excellent separation performance for positional, structural and cis-/trans-isomers. Among them, the column displayed advantageous resolving capability over the commercial polysiloxane stationary phase for aromatic amine isomers. Moreover, the C4A-C10 column showed good column repeatability with RSD values below 0.06% for run-to-run, 0.12-0.27% for day-to-day and 2.8-5.3% for column-to-column.
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