Related Experiment Video
Updated: Jan 17, 2026
08:59
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
Published on: September 27, 2019
12.1K
Facile time-controlled synthesis of two-dimensional Zr-perylenediimide MOF nanosheets for ultrasensitive DNA
Shiyang He1,2, Yuhong Chen2, Jiayi Wang2
1College of Chemistry, Zhengzhou University, Kexue Avenue 100, Zhengzhou, Henan 450001, P. R. China.
Dalton Transactions (Cambridge, England : 2003)
|September 25, 2025
Abstract:
This study reports a surfactant-free synthesis of two-dimensional Zr-perylenediimide (PDI) metal-organic framework nanosheets (∼17 nm thick). Characterization confirms their crystallinity. By exploiting their superior fluorescence quenching and selectivity over the bulk material, we developed a fluorescent biosensor that achieved sensitive target DNA detection and effectively discriminated single-base mismatched DNA and random DNA.
