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Published on: February 28, 2025
[Etiology of ascites in 165 children]
Yong Wang1, Sheng-Hua Wan1, Chun-Lei Zhan1
1Department of Gastroenterology, Jiangxi Children's Hospital, Nanchang 330000, China.
Insights
Common causes of pediatric ascites include surgical acute abdomen, infections, and neoplastic diseases. Etiology varies by age group, impacting diagnosis and treatment strategies for children with ascites.
Area of Science:
- Pediatric Gastroenterology
- Clinical Pediatrics
- Etiology of Ascites
Background:
- Ascites in children presents a diagnostic challenge with diverse underlying causes.
- Understanding the etiological spectrum is crucial for timely and effective management.
Purpose of the Study:
- To investigate the causes and clinical characteristics of ascites in pediatric patients.
- To establish a diagnostic and therapeutic basis for childhood ascites.
Main Methods:
- Retrospective review of medical data from 165 children diagnosed with ascites.
- Data collected from January 1, 2010, to December 31, 2019.
Main Results:
- Surgical acute abdomen and infectious diseases were the most frequent causes (23.6% each), followed by neoplastic diseases (16.4%).
- Etiology varied significantly by age: surgical acute abdomen and hepatogenic diseases predominated in infants, neoplastic disease in young children, and infectious diseases in adolescents.
- The male to female ratio was 1.53:1, with a mean age of onset of 6 years.
Conclusions:
- Surgical acute abdomen, infectious diseases, neoplastic diseases, and hepatogenic diseases are primary contributors to pediatric ascites.
- Age-specific etiological patterns necessitate tailored diagnostic and treatment approaches for children with ascites.
Objectives:
To study the etiology and clinical features of children with ascites, so as to provide a basis for the diagnosis and treatment of ascites in children.
Methods:
The medical data of the children with ascites, who were hospitalized from January 1, 2010 to December 31, 2019, were retrospectively reviewed.
Results:
Among the 165 children with ascites, the male/female ratio was 1.53:1, and the mean age of onset was (6±4) years. The causes of ascites included surgical acute abdomen (39 children, 23.6%), infectious diseases (39 children, 23.6%), neoplastic diseases (27 children, 16.4%), hepatogenic diseases (18 children, 10.9%), pancreatitis (10 children, 6.1%), cardiogenic diseases (8 children, 4.8%), rheumatic immune diseases (6 children, 3.6%), and nephrogenic diseases (5 children, 3.0%). According to the age of onset, there were 33 infants, 24 young children, 30 preschool children, 41 school-aged children, and 37 adolescents. Surgical acute abdomen and hepatogenic diseases were the main causes of ascites in infants (P<0.05). Neoplastic disease was the leading cause in young children (P<0.05). Infectious diseases were the most common cause in adolescents (P<0.05).
Conclusions:
Surgical acute abdomen, infectious diseases, neoplastic diseases, and hepatogenic diseases are the common causes of ascites in children, and there are some differences in the leading cause of ascites between different age groups.
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