Spectrum of congenital lung and foregut malformations: scope for awareness and prompt management-a case series

Vishal Singh1, Gunjan Shoor2, Samir Kant Acharya3

  • 1Department of Radiodiagnosis, ESIC Superspeciality Hospital, Hyderabad, Telangana 500038 India.

Insights

Congenital lung and foregut malformations are often misdiagnosed in India. Early surgical intervention offers good outcomes, but antenatal monitoring needs improvement.

Area of Science:

  • Pediatric Surgery
  • Thoracic Malformations
  • Congenital Abnormalities

Background:

  • Congenital lung and foregut malformations are rare but significant causes of infant morbidity.
  • Most existing literature originates from Western countries, with limited data from India.
  • Misdiagnosis and delayed treatment pose unique challenges in resource-limited settings.

Observation:

  • A retrospective review of 20 patients with thoracic lesions treated at a Delhi tertiary care hospital (March 2017-December 2019).
  • Eight patients had antenatal detection, but none received serial monitoring.
  • Presentations varied, including respiratory distress, pneumonia, and misdiagnosed congenital lobar emphysema.

Findings:

  • Eight patients presented with respiratory distress, three with congenital lobar emphysema misdiagnosed as pneumothorax.
  • Eight patients suffered from pneumonia, with four having prior hospital admissions for undetected congenital pathology.
  • All 20 patients underwent successful surgery with good outcomes and radiological evidence of compensatory lung growth at 6 months.

Implications:

  • Increased antenatal detection necessitates improved serial monitoring protocols.
  • A higher index of suspicion among pediatricians and surgeons is crucial for timely diagnosis.
  • Proactive surgical resection, facilitated by modern anesthesia, leads to favorable outcomes and prevents complications.

Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
162
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
327
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
174
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
230
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
406
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
356