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Murine Ileocolic Bowel Resection with Primary Anastomosis
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Gut microbiota in bariatric surgery.

Amin Gasmi1,2, Geir Bjørklund3, Pavan Kumar Mujawdiya4

  • 1Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France.

Critical Reviews in Food Science and Nutrition
|May 9, 2022
PubMed
Summary

Gut microbes influence bariatric surgery outcomes. Modulating gut microbiota with prebiotics, probiotics, and postbiotics can improve weight loss and reduce complications after surgery.

Keywords:
Gut microbesbariatric surgerypostbioticsprebioticsprobioticsshort-chain fatty acidsvirome

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Area of Science:

  • Microbiology
  • Gastroenterology
  • Metabolic Science

Background:

  • Human survival depends on symbiotic gut microbes performing essential metabolic and physiological functions.
  • Gut dysbiosis, an altered gut microbiota profile, is linked to obesity and metabolic disorders.
  • Bariatric surgery is a primary treatment for obesity, significantly impacting global weight management strategies.

Approach:

  • This review examines the intricate association between gut microbiota and bariatric surgery.
  • It synthesizes scientific evidence highlighting the role of gut microbes in surgical outcomes.
  • The review focuses on how bariatric surgery alters gut microbiota and short-chain fatty acid production.

Key Points:

  • Bariatric surgery demonstrably alters the gut microbiota composition.
  • Gut microbes play a critical role in the positive clinical results observed post-bariatric surgery.
  • Microbiota modulation is key for weight reduction and mitigating adverse events after bariatric procedures.

Conclusions:

  • Gut microbes are integral to the success of bariatric surgery.
  • Interventions like prebiotics, probiotics, and postbiotics can enhance therapeutic outcomes.
  • Understanding this symbiotic relationship is crucial for optimizing obesity management.