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Association Between Stroke Characteristics and Post-Stroke Fatigue: A Meta-Analysis.
Jun Shu1, Yiqing Ren1, Guidong Liu1
1Department of Neurology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Neurology India
|May 9, 2022
Summary
Post-stroke fatigue (PSF) is linked to stroke type but not stroke location. This meta-analysis clarifies that stroke characteristics play a minor role in developing this distressing symptom for survivors.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Clinical Research
Background:
- Post-stroke fatigue (PSF) significantly impacts stroke survivors' quality of life.
- Previous research suggests PSF correlates with mood disturbances like depression and anxiety.
- The relationship between specific stroke characteristics (type and location) and PSF remains insufficiently understood.
Purpose of the Study:
- To conduct a meta-analysis investigating the association between stroke characteristics and post-stroke fatigue.
- To clarify the influence of stroke type and location on the occurrence of PSF.
Main Methods:
- A systematic search of electronic databases (PubMed, Web of Science, Cochrane Library) was performed up to July 9, 2019.
- Eligible studies were evaluated for quality.
- Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated to synthesize findings.
Main Results:
- Eight studies comprising 1816 stroke patients were included.
- PSF showed a significant correlation with stroke type (OR = 2.42, 95% CI = [1.27, 4.61], P = 0.007).
- No significant association was found between stroke location and PSF.
Conclusions:
- Post-stroke fatigue is closely relevant to stroke type.
- Stroke location does not appear to be significantly related to PSF.
- Stroke characteristics may play a minimal role in PSF development; findings require cautious interpretation pending further research.
