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Updated: Sep 24, 2025

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction
Published on: April 10, 2018
ThioCORMates: Tunable and Cost-Effective Carbon Monoxide-Releasing Molecules
Catherine A DeSimone1, S Lyla Naqvi1, Sarah Z Tasker1
1Department of Chemistry, Franklin & Marshall College, 415 Harrisburg Ave, Lancaster, PA 17603, USA.
Abstract:
Carbon monoxide-releasing molecules (CORMs) can offer a safer alternative to CO delivery than the use of CO gas cylinders. Upon treatment with an amine base, S-aryl thioformates ("thioCORMates") release CO nearly quantitatively at room temperature, a gas which can then be harnessed for carbonylative cross-coupling, biological study, or inorganic synthesis. These bench-stable molecules are easily synthesized from the corresponding thiophenol and can be electronically tuned to release CO at different rates-from less than 1 min to greater than 1 h-offering a practical alternative to existing CORM technology. Finally, isotopically labeled 13 CO can be conveniently generated and used, with the thioCORMate synthesized from 13 C-formic acid.
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