Related Experiment Video
Updated: Sep 24, 2025
Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
Published on: June 5, 2019
Pattern Changes in the Heart Rate Variability of Patients Undergoing Coronary Artery Bypass Grafting Surgery
Ngo Van Thanh1, Nguyen Sinh Hien1, Pham Nguyen Son2
1Hanoi Heart Hospital, 92 Tran Hung Dao, Hoan Kiem District, Hanoi 11019, Vietnam.
Insights
Heart rate variability (HRV) significantly decreases after coronary artery bypass grafting (CABG) but largely recovers within three months, indicating autonomic nervous system improvement post-surgery.
Area of Science:
- Cardiology
- Cardiac Surgery
- Autonomic Nervous System Function
Background:
- Coronary artery bypass grafting (CABG) is a primary treatment for coronary artery disease (CAD).
- Post-CABG patients face risks of cardiovascular events and arrhythmias.
- Cardiac arrhythmias are linked to heart rate variability (HRV) changes.
Purpose of the Study:
- To investigate the temporal changes in heart rate variability (HRV) following coronary artery bypass grafting (CABG).
- To understand the pattern of autonomic nervous system recovery after CABG.
Main Methods:
- Prospective study of 119 stable CAD patients undergoing CABG.
- 24-hour Holter recordings were taken pre-surgery and at 1 week, 3 months, and 6 months post-surgery.
- Analysis included time-domain and frequency-domain HRV parameters, focusing on ASDNN and SDNN.
Main Results:
- HRV parameters showed a sharp decline 7 days after CABG (51.8% decrease).
- Most HRV indices recovered by 3 months post-surgery (19.6% decrease).
- Significant improvements in HRV were observed at 6 months compared to pre-operative levels.
Conclusions:
- The early post-CABG HRV decrease is likely due to acute surgical effects.
- HRV recovery at 3 months suggests improvement in autonomic nervous system dysfunction.
- Full recovery of autonomic function and improved reperfusion contribute to enhanced HRV by 6 months post-CABG.
Introduction:
Coronary artery bypass grafting (CABG) with extracorporeal circulation is a key therapy for coronary artery disease (CAD). However, cardiovascular events and cardiac arrhythmias may still occur in these patients following surgery. Many studies have demonstrated a correlation between cardiac arrhythmias and heart rate variability (HRV). This study aimed to establish the temporal change pattern of HRV observed following CABG.
Methods:
A prospective method was used to study 119 consecutive patients with stable CAD who were assessed using 24-hour Holter recordings 2 days before CABG and 1 week, 3 months, and 6 months after the surgery at Hanoi Heart Hospital from June 2016 to August 2018. Main results: All the time-domain and frequency-domain parameters of HRV decreased precipitately after CABG and were mostly recovered 3 months postoperatively. The percentage of decreased HRV before surgery was 28.6% and 51.8% after 7 days, 19.6% after 3 months, and 12.7% after 6 months. ASDNN and SDNN before and after surgery had the highest rates of change.
Conclusion:
The early decrease in HRV observed 7 days after CABG may be related to the acute effects of the surgery. The recovery of HRV at 3 months after surgery, regardless of the preoperative state of the patients, implies that the autonomic nervous system (ANS) disorder may be improved at this time. At 6 months after surgery, the autonomic nervous injury was recovered in combination with improvement of reperfusion, resulting in improvement in almost all HRV indices compared with those indices preoperatively.
More Related Videos
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Related Concept Videos
01:30Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
01:25Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
01:18Dysrhythmias IV: Characteristics of Bradyarrhythmias
01:19Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
01:30Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
01:29Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...