Related Experiment Video
Updated: Sep 23, 2025

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach
Published on: December 4, 2021
Separation performance of p-tert-butyl(tetradecyloxy)calix[6]arene as a stationary phase for capillary gas
Tao Sun1, Xiaomin Shuai2, Yujie Chen1
1College of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University Luoyang 471934 P. R. China suntao2226@163.com suntao@lynu.edu.cn.
Abstract:
This work presents the first example of the utilization of p-tert-butyl(tetradecyloxy)calix[6]arene (C6A-C10) as a stationary phase for capillary gas chromatographic (GC) separation. The statically coated C6A-C10 column showed a column efficiency of 3293 plates per m and had a nonpolar nature. Its selectivity and retention behaviour were investigated using a number of mixtures of diverse analytes and their isomers. As a result, the C6A-C10 column exhibited high resolving capability for aliphatic and aromatic analytes from apolar to polar nature, especially for positional, structural and cis-/trans-isomers. Moreover, the C6A-C10 column showed thermal stability up to 240 °C. In addition, it was applied for the determination of isomer impurities in real samples, proving its good potential for practical GC analysis.
Related Concept Videos
Gas Chromatography: Types of Columns and Stationary Phases
For an analyte to remain on the column for a sufficient amount of time, it must exhibit some level of compatibility (or...
High-Performance Liquid Chromatography: Introduction
In HPLC, two phases play a critical role in the separation process:
Gas Chromatography: Introduction
In GC, a sample is vaporized and mixed with an inert carrier gas (the mobile phase), which transports it through a...
Capillary Electrophoresis: Applications
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Silica Gel Column Chromatography: Overview
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
Size-Exclusion Chromatography
Silica particles offer advantages such as rigidity,...

