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Updated: Sep 23, 2025

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Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
Published on: December 8, 2015
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Emerging Liquid Metal Biomaterials: From Design to Application
Luyang Wang1, Runze Lai1, Lichen Zhang1
1College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Advanced Materials (Deerfield Beach, Fla.)
|May 12, 2022
Summary
Liquid metals (LMs) offer unique advantages as biomaterials for diverse biomedical applications. Their structural design and functionalization enhance therapeutic effects, driving innovation in medicine.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Medical Devices
Background:
- Liquid metals (LMs) are emerging biomaterials with excellent biosafety, fluidity, and conductivity.
- These properties make LMs suitable for drug delivery, tumor therapy, bioimaging, and biosensors.
Purpose of the Study:
- To present the advantages of LMs in biomedicine.
- To explore the design of LM-based biomaterials across various scales.
- To summarize advanced progress and discuss challenges and prospects.
Main Methods:
- Reviewing the properties and applications of LMs in biomedical fields.
- Analyzing the structure-property relationships of LM-based biomaterials.
- Summarizing recent advancements and future outlooks.
Main Results:
- LMs offer a versatile platform for biomedical applications due to their unique properties.
- Structural design and functionalization enhance LM capabilities for targeted and stimuli-responsive therapies.
- Progress in LM-based biomaterials spans micro/nano to macroscales, optimizing performance.
Conclusions:
- Liquid metals represent a promising class of biomaterials with significant potential in advanced medical applications.
- Further research into LM design and functionalization will unlock multifunctional synergistic therapeutic effects.
- Addressing current challenges will pave the way for broader clinical translation of LM-based technologies.

