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Challenges and complexities in evaluating severe acute respiratory syndrome coronavirus 2 molecular diagnostics

Lesley E Scott1, Lara D Noble1, Ashika Singh-Moodley1,2

  • 1Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

African Journal of Laboratory Medicine
|May 13, 2022
PubMed
Abstract

No abstract available in PubMed .

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Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...

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