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Multi-species Conserved Sequences

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale studies have provided new insights into the evolutionary relationship between organisms.
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Related Experiment Video

Updated: Sep 23, 2025

RNA-Seq Analysis of Differential Gene Expression in Electroporated Chick Embryonic Spinal Cord

RNA-Seq Analysis of Differential Gene Expression in Electroporated Chick Embryonic Spinal Cord

Published on: November 1, 2014

Galbase: a comprehensive repository for integrating chicken multi-omics data.

Weiwei Fu¹, Rui Wang¹, Naiyi Xu¹

¹Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.

|May 13, 2022

Summary

This summary is machine-generated.

Galbase integrates chicken multi-omics data, offering a valuable resource for identifying genetic variations linked to complex traits and advancing poultry research and breeding.

Keywords:

Chicken Complex traits Database Omics data

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Area of Science:

Genomics
Bioinformatics
Animal Science

Background:

Multi-omics data integration is crucial for understanding complex traits.
Limited integration of multi-omics resources hinders research in non-mammalian species like chickens.

Purpose of the Study:

To construct a centralized, accessible repository for chicken multi-omics data.
To facilitate genetic research and breeding processes in chickens.

Main Methods:

Integrated public chicken multi-omics data from 928 genomes, 429 transcriptomes, 379 epigenomes, and extensive QTL and association entries.
Included millions of genetic variations (SNPs, InDels) and cis-regulatory elements.
Incorporated visualization tools (maps, heatmaps, peak patterns) and annotation modules.

Main Results:

Developed Galbase, a comprehensive repository of chicken genomic, transcriptomic, and epigenomic data.
Enabled retrieval of genomic variations, gene expression, and epigenomic signals.
Provided integrated tools for sequence feature analysis, including genome browsers and BLAST.

Conclusions:

Galbase offers new opportunities for functional genomic studies in chickens.
The resource aids in identifying genetic variations underlying complex traits.
Galbase is publicly accessible, supporting the poultry research community.