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Updated: Sep 23, 2025

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
Developing guideline-based key performance indicators for recurrent miscarriage care: lessons from a multi-stage
Marita Hennessy1,2,3, Laura Linehan4,5,6, Rebecca Dennehy4,5,6
1Pregnancy Loss Research Group, Department of Obstetrics and Gynaecology, University College Cork, Cork, T12 DC4A, Ireland. maritahennessy@ucc.ie.
Developing guideline-based key performance indicators (KPIs) for recurrent miscarriage care is feasible with diverse stakeholder input. This study prioritized 110 KPIs to improve national services for recurrent miscarriage.
Area of Science:
- Reproductive Medicine
- Healthcare Quality Improvement
- Clinical Governance
Background:
- Recurrent miscarriage care lacks standardized pathways, leading to inconsistent clinical practice.
- There is a need for guideline-based key performance indicators (KPIs) to evaluate national recurrent miscarriage services.
- Previous KPI development exercises have often excluded diverse stakeholder groups.
Purpose of the Study:
- To outline the process and experiences of developing guideline-based KPIs for recurrent miscarriage care.
- To involve a diverse stakeholder group in creating KPIs for evaluating national services.
- To address the inconsistency and poor organization in current recurrent miscarriage care.
Main Methods:
- Systematic review of clinical practice guidelines for recurrent miscarriage care.
- Modified e-Delphi survey and virtual meetings with diverse stakeholders to achieve consensus.
- Development and prioritization of candidate KPIs through participatory methods.
Main Results:
- 110 KPIs were prioritized from an initial list of 373 recommendations and 14 outcomes.
- KPIs cover structure of care (20), counseling (7), investigations (30), treatment (34), and outcomes (19).
- Stakeholder feedback highlighted accessibility, diversity, and streamlining as key process themes.
Conclusions:
- Developing guideline-based KPIs with diverse stakeholders is both important and feasible.
- A suite of 110 prioritized KPIs is established for recurrent miscarriage care evaluation.
- This experience can guide similar KPI development projects, especially those lacking clinical guidelines or involving multiple stakeholders.
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Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
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