[State of intracardiac hemodynamics in normothermic heart perfusion]

The state of intracardiac hemodynamics during normothermal perfusion was studied on an isolated heart-lung preparation obtained by the Robicsek I method (30 experiments). In appraisal of the hemodynamic and myocardial indices characterizing the functional condition of the right and left ventricles in 2 to 3 hours, definite changes were revealed which allowed prognostication of the duration and effectiveness of preservation. If the functional condition of the transplant (changes predominantly in the right ventricle) diminished in this period, heart arrest occurred within the next 30--60 minutes. If after these 2--3 hours the work of the heart-lung preparation was characterized by stationary parameters of intracardiac hemodynamics, such a transplant was capable of maintaining autoperfusion for 7 to 8 hours; the optimum term of preservation, however, was 6 hours. Irreparable diminution of the transplant viability occurred sharply in the next one or two hours.