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Consensus on MR Imaging of Endolymphatic Hydrops in Patients With Suspected Hydropic Ear Disease (Meniere)
Yupeng Liu1,2,3, Ilmari Pyykkö4, Shinji Naganawa5
1Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Abstract:
Endolymphatic hydrops (EH) is considered the histological hallmark of Meniere's disease. Visualization of EH has been achieved by special sequences of inner ear magnetic resonance imaging (MRI) with a gadolinium-based contrast agent via intravenous or intratympanic administration. Although it has been applied for more than 10 years since 2007, a unified view on this technique has not yet been achieved. This paper presents an expert consensus on MRI of endolymphatic hydrops in the following aspects: indications and contra-indications for patient selection, methods of contrast-agent administration (intravenous or intratympanic), MRI sequence selection, the specific scanning parameter settings, and standard image evaluation methods and their advantages and disadvantages. For each part of this consensus, a comment is attached to elucidate the reasons for the recommendation.
Insights
This expert consensus provides guidelines for Magnetic Resonance Imaging (MRI) to visualize endolymphatic hydrops (EH), a key indicator of Meniere's disease, using contrast agents.
Area of Science:
- Otolaryngology
- Radiology
- Neuroscience
Background:
- Endolymphatic hydrops (EH) is the defining histological feature of Meniere's disease.
- Magnetic Resonance Imaging (MRI) with contrast agents enables visualization of EH.
- Current application of MRI for EH lacks a unified expert consensus.
Purpose of the Study:
- To establish an expert consensus on the MRI technique for visualizing endolymphatic hydrops (EH).
- To standardize MRI protocols for diagnosing Meniere's disease.
- To provide recommendations on patient selection, contrast administration, and image evaluation.
Main Methods:
- Review and synthesis of existing literature and expert opinion.
- Development of consensus guidelines covering indications, contraindications, and contrast administration routes (intravenous vs. intratympanic).
- Standardization of MRI sequences, scanning parameters, and image interpretation methods.
Main Results:
- Detailed recommendations are provided for each aspect of the MRI procedure for EH.
- Advantages and disadvantages of different methods and techniques are discussed.
- Rationale for each recommendation is elucidated in attached comments.
Conclusions:
- A unified expert consensus on MRI for endolymphatic hydrops is presented.
- These guidelines aim to improve diagnostic accuracy and consistency for Meniere's disease.
- Standardized MRI protocols will enhance the clinical utility of this imaging technique.
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