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Related Experiment Video

Updated: Sep 23, 2025

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

HDL and Surgery.

Yue-Ming Peng^1,2,3, Jing-Song Ou^4,5,6

¹Division of Cardiac Surgery, Heart Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.

Advances in Experimental Medicine and Biology

|May 16, 2022

Summary

This summary is machine-generated.

High-density lipoprotein (HDL) function is crucial post-surgery. Changes in HDL amount, components, and function occur after bariatric and cardiac surgeries, impacting clinical predictions.

Keywords:

Bariatric surgery Cardiac surgery HDL Small HDL subfractions

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Last Updated: Sep 23, 2025

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Published on: December 22, 2023

Area of Science:

Cardiovascular Science
Metabolic Surgery
Clinical Biochemistry

Background:

Plasma high-density lipoprotein (HDL) possesses functions beyond lipid transport.
The role of HDL in the postsurgery period is increasingly recognized.
Surgical interventions significantly impact physiological parameters.

Purpose of the Study:

To summarize alterations in HDL characteristics following major surgeries.
To highlight the functional and compositional changes in HDL post-surgery.
To identify key HDL-related biomarkers for postsurgical outcomes.

Main Methods:

Literature review of studies investigating HDL changes after bariatric and cardiac surgery.
Analysis of data on HDL quantity, composition, and functional capacity.
Evaluation of established and emerging HDL-related clinical predictors.

Main Results:

Significant changes in HDL quantity and quality are observed after bariatric and cardiac surgeries.
HDL components and functional properties, such as cholesterol efflux capacity, are altered.
Specific HDL-related indices, including HDL cholesterol (HDL-C) concentration and monocyte count to HDL ratio (MHR), show predictive value.

Conclusions:

HDL plays a critical role in the postsurgical period, with significant modifications occurring after various surgeries.
Changes in HDL quantity, composition, and function are important considerations for patient recovery.
HDL-derived biomarkers are valuable for predicting clinical outcomes in the postsurgery setting.