Related Experiment Video
Updated: Sep 23, 2025

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
Improved distribution of leg forces after fibular resection and synostosis
Tariq Rahman1, Geovanny Oleas-Santillan2, Jinyong Wee3
1Department of Biomedical Research, Nemours Children's Hospital Delaware, 5424 E400 Experimental Station, 200 Powder Mill Road, Wilmington, DE, 19803, USA. trahman@nemours.org.
Purpose:
Genu varum- a common symptom in achondroplasia- may lead to ankle valgus in children. Ankle valgus may be mitigated by tibiofibular synostosis, but this is not always the case. The mechanical environment around the growth plates plays an important role in ankle valgus. The purpose of this project is 1) to determine the strain through the distal fibular growth plate before and after tibiofibular synostosis, and 2) postulate whether the change in strain affects ankle valgus. This project measured the distal fibular strain in a porcine hind leg model.
Methods:
The lower legs of seven pigs were removed, instrumented with strain gauges, and loaded compressively in a material testing machine. Loads were applied at three phases: 1) the intact leg, 2) leg with fibula resected, and 3) leg with fibula resected and tibiofibular synostosis. Mean strains were compared between phases using a mixed affect model. The significance level was adjusted for multiple comparisons using the Bonferroni method.
Results:
Phase 1, intact leg, had the highest strain value at 1247.9μɛ. In phase 2, the mean strain was 106.2μɛ. In phase 3, the compressive mean strain dropped to 477.4μɛ, which is 38% of the strain in phase 1. Standard error was 86.8μɛ; p < 0.001.
Conclusion:
Results indicate that more of the force through the leg is transmitted through the tibia after fibular resection and tibiofibular synostosis, which improves the balance of forces through the leg.
More Related Videos
09:26An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur
Published on: October 23, 2017
06:38Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016
Related Concept Videos
Bones of the Lower Limb: Tibia and Fibula
Bones of the Lower Limb: Femur and Patella