Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

940
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
940
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

46
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
46
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

49
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
49
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

33
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
33
Disorders of Hemostasis01:24

Disorders of Hemostasis

1.2K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.2K
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

509
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
509

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage.

The New England journal of medicine·2026
Same author

Comparison of Visual Performance and Patient Satisfaction Between Two Trifocal Intraocular Lenses: A Prospective, Paired-Eye Comparative Study.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Mitsugumin 53 protects against smoke inhalation lung injury via suppressing the proinflammatory response in a rat model.

Free radical biology & medicine·2026
Same author

P2Y12 Assay Identifies Patients at Risk for Blood Transfusion Following Cardiac Surgery.

The Journal of surgical research·2025
Same author

Age-Related Changes in Endothelial Cell Density of the Central and Peripheral Corneal Endothelium.

Cornea·2025
Same author

Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD.

Investigative ophthalmology & visual science·2025
Same journal

Learning Surgery's Moral Questions: Mentorship, Reflection, and Professional Formation.

The American surgeon·2026
Same journal

Complete Response of Merkel Cell Carcinoma to Immunotherapy and Single-Fraction Radiotherapy Following Severe COVID-19 Infection: A Case Report and Review of Immune Mechanism.

The American surgeon·2026
Same journal

Perioperative Acute Myocardial Infarction in Non-Cardiac Operations: A National Analysis.

The American surgeon·2026
Same journal

Outcomes of Completion Cholecystectomy: Association With Patient Comorbidity in a National Database.

The American surgeon·2026
Same journal

Building the Conversation: Editorial Stewardship in Contemporary Surgical Publishing.

The American surgeon·2026
Same journal

Musculoskeletal Pain in Surgeons on Operating Days.

The American surgeon·2026
See all related articles

Related Experiment Video

Updated: Sep 23, 2025

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
06:28

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

6.9K

Thromboelastography-Based Evaluation of Gender-Associated Hypercoagulability.

Skylar C Rodgers1, Kristen T Carter1, Deepti Patki1

  • 1Department of Surgery, 8083University of Mississippi Medical Center, Jackson, MS, USA.

The American Surgeon
|May 16, 2022
PubMed
Summary
This summary is machine-generated.

Women exhibit hypercoagulable blood clot formation compared to men, indicated by faster fibrin deposition and stronger clots. This gender difference in coagulation persists even after adjusting for age and race.

Keywords:
gender dimorphismhypercoagulabilitythromboelastography

More Related Videos

Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients
04:56

Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients

Published on: August 4, 2023

884
In Vitro Thrombosis Test for Ventricular Assist Devices
09:15

In Vitro Thrombosis Test for Ventricular Assist Devices

Published on: March 21, 2025

796

Related Experiment Videos

Last Updated: Sep 23, 2025

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
06:28

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

6.9K
Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients
04:56

Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients

Published on: August 4, 2023

884
In Vitro Thrombosis Test for Ventricular Assist Devices
09:15

In Vitro Thrombosis Test for Ventricular Assist Devices

Published on: March 21, 2025

796

Area of Science:

  • Coagulation science
  • Hematology
  • Biomedical research

Background:

  • Previous studies noted age, race, and gender variations in coagulation.
  • A lack of rigorous multivariate analysis adjusting for these factors existed.
  • This study aimed to clarify these demographic influences on baseline coagulation.

Purpose of the Study:

  • To investigate the effects of age, race, and gender on the baseline coagulation status of healthy volunteers.
  • To perform a multivariate analysis adjusting for age, race, and gender.
  • To identify gender-specific differences in coagulation parameters.

Main Methods:

  • Recruited 30 healthy volunteers with no history of bleeding or thrombotic events.
  • Collected citrated and heparinized blood samples.
  • Performed kaolin and platelet-mapping thromboelastography (TEG) assays.

Main Results:

  • Participants had a mean age of 37, BMI of 29 kg/m², 47% were African-American, and 70% were female.
  • Women were significantly older than men (40 vs. 28 years, P = .002).
  • Multivariate analysis revealed gender differences in hypercoagulability (Pillai's trace P = .02), with women showing shorter K-time, steeper alpha angle, higher maximal amplitude, and larger G parameter.

Conclusions:

  • Women exhibit relatively hypercoagulable fibrin deposition kinetics, platelet contributions, and clot strength compared to men, independent of age and race.
  • Further research is required to understand clinical implications and tailor therapies for gender-associated hypercoagulability.