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Hypertension and infant outcomes: North Carolina pregnancy risks assessment monitoring system data

Forgive Avorgbedor1, Susan Silva2, Thomas P McCoy2

  • 1University of North Carolina at Greensboro School of Nursing, United States; School of Nursing, Duke University, Durham, NC, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States; University of North Carolina at Chapel- Hill School of Nursing, United States.

Pregnancy Hypertension
|May 16, 2022
PubMed

This study examined the risk factors that moderate the relationship between hypertension and infant outcomes or were independent risk factors in a large and diverse sample of pregnant women with and without hypertension before conception. The sample included 2,996 women, where 197 had hypertension. Black women comprised 35.5% of the hypertension group relative to 19.7% of non-hypertension. Women with hypertension were more likely to have more preterm births (17.7% vs. 7.4%; ARR = 1.91, p <.001) and have infants with low birth weights (16.8% vs. 6.7%; ARR = 2.26, p <.001), independent of other maternal risk factors in logistic modeling. Maternal Black race versus White also was independently associated with preterm birth (ARR = 1.42, p =.045) and low birth weight (ARR = 1.72, p <.001). Maternal age and race did not significantly moderate the effects of hypertension on infant outcomes, but both Black race and hypertension status were independently associated with adverse birth outcomes.

Keywords:
Black womenHypertensionMaternal agePreterm infantsSmall for gestational age infants

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