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mTOR substrate phosphorylation in growth control

Stefania Battaglioni1, Don Benjamin1, Matthias Wälchli1

  • 1Biozentrum, University of Basel, Spitalstrasse 41, 4056 Basel, Switzerland.

Cell
|May 17, 2022
PubMed
Summary

The target of rapamycin (TOR) kinase regulates cell growth and metabolism. Mammalian TOR complexes mTORC1 and mTORC2 phosphorylate distinct substrates using a common motif, despite sharing a catalytic subunit.

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