Related Experiment Video
Updated: Sep 23, 2025

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
Chronotype at the beginning of secondary school and school timing are both associated with chronotype development
Guadalupe Rodríguez Ferrante1,2, Andrea Paula Goldin1, Mariano Sigman1,3
1Laboratorio de Neurociencia, Universidad Torcuato Di Tella, CONICET, Av. Figueroa Alcorta, C1428BCW, CABA, C1428BIJ7350, Buenos Aires, Argentina.
Abstract:
The misalignment between late chronotypes and early school start times affect health, performance and psychological well-being of adolescents. Here we test whether, and how, the baseline chronotype (i.e. chronotype at the beginning of secondary school) and the school timing affect the magnitude and the direction of the developmental change in chronotype during adolescence. We evaluated a sample of Argentinian students (n = 259) who were randomly assigned to attend school in the morning (07:45 a.m.-12:05 p.m.), afternoon (12:40 p.m.-05:00 p.m.) or evening (05:20 p.m.-09:40 p.m.) school timings. Importantly, chronotype and sleep habits were assessed longitudinally in the same group of students along secondary school (at 13-14 y.o. and 17-18 y.o.). Our results show that: (1) although chronotypes partially align with class time, this effect is insufficient to fully account for the differences observed in sleep-related variables between school timings; (2) both school timing and baseline chronotype are independently associated with the direction and the magnitude of change in chronotype, with greater delays related to earlier baseline chronotypes and later school timings. The practical implications of these results are challenging and should be considered in the design of future educational timing policies to improve adolescents' well-being.
Related Concept Videos
Signs of Puberty
Cognitive Development During Adolescence
Circadian Rhythms and Gene Regulation
Biological Clocks and Seasonal Responses
Socioemotional Experience and Gender Development
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...

