Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Anchoring-and-Adjustment Heuristic01:25

The Anchoring-and-Adjustment Heuristic

7.4K
In order to make good decisions, we use our knowledge and our reasoning. Often, this knowledge and reasoning is sound and solid. However, sometimes, we are swayed by biases or by others manipulating a situation. For example, let’s say you and three friends wanted to rent a house and had a combined target budget of $1,600. The realtor shows you only very run-down houses for $1,600 and then shows you a very nice house for $2,000. Might you ask each person to pay more in rent to get the...
7.4K
Lipids as Anchors01:32

Lipids as Anchors

5.9K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
5.9K
Regression Analysis01:11

Regression Analysis

6.1K
Regression analysis is a statistical tool that describes a mathematical relationship between a dependent variable and one or more independent variables.
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
6.1K
Regression Toward the Mean01:52

Regression Toward the Mean

6.5K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.5K
Multiple Regression01:25

Multiple Regression

3.2K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
3.2K
Anchoring Junctions01:03

Anchoring Junctions

4.0K
Anchoring junctions are multiprotein complexes that help cells connect to other cells and the extracellular matrix. Anchoring junctions are present on the lateral and basal surfaces of cells, providing strong and flexible connections. Focal adhesions are often formed due to cell interactions with the ECM substrata, which initiate signal transduction via kinase cascades and other mechanisms. Together, they provide stability and tissue integrity. There are three types of anchoring junctions:...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ratio of Left Atrial and Ventricular Volume as New Marker of Atrial Cardiopathy and Stroke Risk.

Stroke·2026
Same author

Comment on "Double robust conditional independence test for novel biomarkers given established risk factors with survival data".

Biometrics·2026
Same author

Early Thrombolysis and Outcomes in Central Retinal Artery Occlusion: An Individual Participant Data Meta-Analysis.

Stroke·2025
Same author

Higher-Order Least Squares: Assessing Partial Goodness of Fit of Linear Causal Models.

Journal of the American Statistical Association·2024
Same author

ricu: R's interface to intensive care data.

GigaScience·2023
Same author

Deep Learning Versus Neurologists: Functional Outcome Prediction in LVO Stroke Patients Undergoing Mechanical Thrombectomy.

Stroke·2023
Same journal

Neural posterior estimation on exponential random graph models: evaluating bias and implementation challenges.

Statistics and computing·2026
Same journal

Subgroup Analysis of Differential Networks with Latent Variables.

Statistics and computing·2026
Same journal

Non-negative matrix factorization algorithms generally improve topic model fits.

Statistics and computing·2026
Same journal

Approximating evidence via bounded harmonic means.

Statistics and computing·2026
Same journal

Efficient Inference in First Passage Time Models.

Statistics and computing·2026
Same journal

Optimal <i>F</i>-score Matching for Bipartite Record Linkage.

Statistics and computing·2026
See all related articles

Related Experiment Video

Updated: Sep 22, 2025

Foreign Accent and Forensic Speaker Identification in Voice Lineups: The Influence of Acoustic Features Based on Prosody
09:09

Foreign Accent and Forensic Speaker Identification in Voice Lineups: The Influence of Acoustic Features Based on Prosody

Published on: September 27, 2024

547

Distributional anchor regression.

Lucas Kook1,2, Beate Sick1,2, Peter Bühlmann3

  • 1Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland.

Statistics and Computing
|May 18, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces distributional anchor regression, a novel method enhancing out-of-distribution (OOD) generalization for prediction models. It extends causal regularization to handle censored and ordinal data, improving robustness against data shifts.

Keywords:
Anchor regressionCovariate shiftDiluted causalityDistributional regressionOut-of-distribution generalizationTransformation models

More Related Videos

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

3.4K
Installation Method to Enhance Quality Control for Fiber Reinforced Polymer Spike Anchors
06:21

Installation Method to Enhance Quality Control for Fiber Reinforced Polymer Spike Anchors

Published on: April 10, 2018

7.2K

Related Experiment Videos

Last Updated: Sep 22, 2025

Foreign Accent and Forensic Speaker Identification in Voice Lineups: The Influence of Acoustic Features Based on Prosody
09:09

Foreign Accent and Forensic Speaker Identification in Voice Lineups: The Influence of Acoustic Features Based on Prosody

Published on: September 27, 2024

547
Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

3.4K
Installation Method to Enhance Quality Control for Fiber Reinforced Polymer Spike Anchors
06:21

Installation Method to Enhance Quality Control for Fiber Reinforced Polymer Spike Anchors

Published on: April 10, 2018

7.2K

Area of Science:

  • Causal inference
  • Statistical modeling
  • Machine learning

Background:

  • Prediction models often fail with out-of-distribution (OOD) data due to differing data distributions.
  • Achieving OOD generalization typically requires strong assumptions about the data generating process (DGP).
  • Anchor regression offers protection against distributional shifts using causal regularization but is limited to squared-error loss.

Purpose of the Study:

  • To generalize anchor regression for OOD generalization to censored and ordinal response variables.
  • To develop a distributional version of anchor regression applicable to a wider range of data types.
  • To assess the capabilities of the proposed method for OOD generalization.

Main Methods:

  • Proposed a distributional anchor regression framework.
  • Combined parametric transformation models for distributional regression with causal regularization.
  • Utilized a generalized notion of residuals for censored and ordered response spaces.

Main Results:

  • Demonstrated the applicability of the distributional anchor regression method.
  • Showcased improved OOD generalization capabilities in exemplary applications and simulations.
  • Validated the method's effectiveness for handling censored and ordinal data.

Conclusions:

  • Distributional anchor regression successfully extends causal regularization to censored and ordinal data.
  • The proposed method enhances OOD generalization beyond the limitations of previous anchor regression techniques.
  • This work broadens the scope of causal methods for robust prediction models.