Medication Adherence Rate in Arab Patients With Cardiovascular Disease: A Systematic Review

Albara Alomari1, Ibrahim Alananzeh2, Heidi Lord3

  • 1Hamad Medical Corporation, Doha, Qatar.

Insights

Medication adherence in Arab patients with cardiovascular disease (CVD) is low, with only 53.2% adhering to treatment. Nonadherence stems from personal factors, treatment complexity, and structural barriers, highlighting the need for family involvement.

Area of Science:

  • Public Health
  • Cardiology
  • Pharmacology

Background:

  • Cardiovascular disease (CVD) is a prevalent chronic illness in the Eastern Mediterranean region.
  • Limited research exists on medication adherence among Arab populations with CVD.

Purpose of the Study:

  • To determine the rates of medication adherence in Arab patients diagnosed with cardiovascular disease.
  • To identify the primary reasons contributing to medication nonadherence in this demographic.

Main Methods:

  • A systematic review was conducted following the Joanna Briggs Institute methodology for prevalence studies.
  • A comprehensive literature search was performed across multiple databases including MEDLINE, EMCARE, CINAHL, Scopus, Science Direct, PsychINFO, and the Cochrane Central Register of Controlled Trials.

Main Results:

  • Thirteen quantitative studies involving Arab adult CVD patients were included in the review.
  • Pooled analysis of nine studies revealed a medication adherence rate of 53.2% (95% CI [51.2%, 55.1%]).
  • Key factors for nonadherence included personal issues, comprehension difficulties, complex treatment regimens, insufficient medication knowledge, and systemic barriers.

Conclusions:

  • Medication adherence in Arab CVD patients exhibits a social gradient.
  • Future strategies to enhance medication adherence should actively involve family members.
Abstract

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