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Updated: Sep 22, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
[Targeted therapies and non-small cell carcinomas : novelties]
Roberta Stauber1, Louis Gro S1, Tu Nguyen-Ngoc1
1Service d'oncologie médicale, Département d'oncologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
In recent years, new therapeutic strategies for non-small cell lung cancer (NSCLC) have been developed, stemming from a better understanding of oncogenic signaling pathways. The analysis of the alterations of genes involved in NSCLC oncogenesis is now an integral part of the diagnostic approach and opens the way to so-called "targeted" therapies. In this article, we will share the latest therapeutic advances by focusing on alterations of HER2, MET, EGFR and KRAS genes, for which new dedicated treatments have become available.
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