Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

621
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
621
Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

823
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
823
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

547
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
547
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

405
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
405
Gastric Motility01:16

Gastric Motility

1.3K
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
1.3K
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

426
Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
426

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Dynamics of Polyglutamine-Expanded ATXN3 in Biofluids of Spinocerebellar Ataxia Type 3.

Movement disorders : official journal of the Movement Disorder Society·2026
Same author

Consensus expert recommendations for management of dysphagia during hospital admission in Parkinson's disease.

Journal of Parkinson's disease·2026
Same author

Thermoregulatory Dysfunction in Parkinson's Disease: Mechanisms, Implications, and Therapeutic Perspectives.

Cells·2025
Same author

Consensus practice recommendations for management of gastrointestinal dysfunction in Parkinson disease.

Parkinsonism & related disorders·2024
Same author

Neurogastroenterology.

Seminars in neurology·2023
Same author

Gastrointestinal Dysfunction in Parkinson's Disease.

Drugs·2022
Same journal

Health-Related Quality of Life in Children with Primary Complex Motor Stereotypies.

Movement disorders clinical practice·2026
Same journal

7 T MRI Connectivity-Guided Reprogramming Improves Deep Brain Stimulation Motor Outcome in Parkinson's Disease.

Movement disorders clinical practice·2026
Same journal

Cutis Verticis Gyrata in SPG11-Related Hereditary Spastic Paraplegia: A Potential Novel Association.

Movement disorders clinical practice·2026
Same journal

"Familial Is Not Always Genetic: Two Brothers with Dystonia and Oculomotor Apraxia Secondary to Rh Incompatibility-Induced Kernicterus".

Movement disorders clinical practice·2026
Same journal

L'inquiétude des jambes: A Forgotten 19th-Century Description of Restless Legs by Antoine Spring.

Movement disorders clinical practice·2026
Same journal

Orthostatic Myoclonus-Clinical and Electrophysiological Features in a Large Retrospective Cohort.

Movement disorders clinical practice·2026
See all related articles

Related Experiment Video

Updated: Sep 22, 2025

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

22.3K

Movement Disorders and the Gut: A Review.

Lauren S Talman1, Ronald F Pfeiffer1

  • 1Department of Neurology Oregon Health & Science University Portland Oregon USA.

Movement Disorders Clinical Practice
|May 19, 2022
PubMed
Summary
This summary is machine-generated.

Movement disorders and gastrointestinal dysfunction are closely linked. This review explores these gastrointestinal symptoms in various movement disorders and related conditions.

Keywords:
gastrointestinalmovement disorders

More Related Videos

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes
06:01

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes

Published on: July 26, 2024

751
Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

14.2K

Related Experiment Videos

Last Updated: Sep 22, 2025

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

22.3K
Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes
06:01

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes

Published on: July 26, 2024

751
Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

14.2K

Area of Science:

  • Neurology
  • Gastroenterology

Background:

  • Gastrointestinal dysfunction is frequently observed in patients with movement disorders.
  • Gastrointestinal symptoms can manifest before or after the onset of neurological symptoms.

Purpose of the Study:

  • To review the gastrointestinal manifestations associated with various movement disorders.
  • To discuss disorders with overlapping gastrointestinal and movement abnormalities.

Main Methods:

  • Literature review of studies on movement disorders and gastrointestinal dysfunction.
  • Analysis of the temporal relationship between gastrointestinal and neurological symptoms.

Main Results:

  • A significant association exists between a range of movement disorders and gastrointestinal issues.
  • Gastrointestinal symptoms are common in both well-known and less common movement disorders.
  • Certain conditions, not primarily classified as movement disorders, present with concurrent GI and motor symptoms.

Conclusions:

  • The interplay between the gut and the nervous system is crucial in understanding movement disorders.
  • Recognizing gastrointestinal symptoms can aid in the diagnosis and management of movement disorders.
  • Further research into the shared pathophysiology of gastrointestinal and movement abnormalities is warranted.