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Updated: Sep 22, 2025

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization
Published on: June 19, 2015
Synthesis and Aggregation of Double Hydrophilic Diblock Glycopolymers via Aqueous SET-LRP
Qiang Zhang1, Paul Wilson1,2, Athina Anastasaki1
1Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Abstract:
A chemically unprotected mannose-containing acrylate (ManA) monomer was synthesized and polymerized by Cu(0)-mediated radical polymerization in water (SET-LRP). One-pot block copolymerization was achieved upon addition of a solution of N-isopropylacrylamide (NIPAm) or diethylene glycol ethyl ether acrylate (DEGEEA) forming thermoresponsive double hydrophilic diblock glycopolymers which revealed self-assembly properties in aqueous solution forming well-defined, sugar-decorated nanoparticles.
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