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Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....

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Predicting malignancy in small testicular lesions.

Octavio José Del Real¹, Carlos Ignacio Calvo de la Barra², Jaime Andrés Jiménez²

¹Department of Urology, Hospital Félix Bulnes Cerda, University of Santiago, Santiago, Chile.

Central European Journal of Urology

|May 20, 2022

Summary

This summary is machine-generated.

Small testicular lesions (STL) detected by ultrasound are often benign, but this study found 69% were malignant. Size and multifocality predict cancer, warranting surgical evaluation for most cases.

Keywords:

biopsy orchiectomy small testicular mass testicular neoplasms testis ultrasonography

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Area of Science:

Urology
Radiology
Oncology

Background:

Small testicular lesions (STL) ≤20 mm detected by ultrasound (US) are often non-palpable.
Up to 80% of these lesions are typically benign, leading to varied management strategies.
Predicting malignancy in STL remains a clinical challenge.

Purpose of the Study:

To determine the proportion of benign lesions among testicular tumors ≤20 mm detected by US.
To identify predictors of malignancy in these small testicular lesions.

Main Methods:

Retrospective descriptive study of orchiectomies for testicular tumors in patients >15 years (2005-2019).
Included patients with lesions ≤20 mm on US imaging.
Analyzed lesion size, palpability, tumor markers, and multifocality for malignancy prediction.

Main Results:

70 patients with STL were included; 69% of lesions were malignant.
Lesions ≤10 mm had a 61% malignancy rate, with non-palpable ≤10 mm lesions showing 50% malignancy.
Multifocal tumors had an 88% malignancy rate; US size and multifocality significantly predicted malignancy.

Conclusions:

Ultrasound maximum size and multifocality are key predictors of malignancy in small testicular lesions.
Even the smallest lesions (≤10 mm) have a significant (50%) chance of being malignant.
Surgical intervention, with or without intraoperative biopsy, is recommended for most small testicular lesions.