Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Monogastric Digestion?01:50

What is Monogastric Digestion?

72.6K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
72.6K
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

230
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
230
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

74
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
74

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sphingolipid Expression During Corneal Wound Healing in a Sphingosine Kinase 1 Knockout Model.

Cells·2026
Same author

Dynamics of genetic and somatic trade-offs in ageing and mortality.

Nature·2026
Same author

Evaluating Outcomes in Patients With Ankylosing Spondylitis Seeking Acute Care By Utilizing Elixhauser Comorbidity Index: An Analysis of Cerner Health Facts Database From 2000 to 2017.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2026
Same author

Kidney Biorepositories: Valuable Tools Advancing Acute Kidney Injury Research.

Kidney360·2025
Same author

A community pharmacy vaccination nudge intervention: Final results of a nationwide study.

Research in social & administrative pharmacy : RSAP·2025
Same author

R-spondin 2 suppresses hepatic steatosis via activation of AMPK-ACC signaling.

JHEP reports : innovation in hepatology·2025

Related Experiment Video

Updated: Sep 22, 2025

Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

4.4K

Circulating Microbiota in Cardiometabolic Disease.

Keiichi Sumida1, Zhongji Han1, Chi-Yang Chiu2

  • 1Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.

Frontiers in Cellular and Infection Microbiology
|May 20, 2022
PubMed
Summary

Circulating microbiota, microorganisms in the bloodstream, are increasingly linked to chronic inflammation and cardiometabolic diseases like diabetes and kidney disease. Understanding their role is crucial for disease management.

Keywords:
cardiometabolic diseasecardiovascular diseasechronic kidney diseasecirculating microbiotadiabetes mellitusend-stage kidney diseasegut microbiotainflammation

More Related Videos

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.7K
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.7K

Related Experiment Videos

Last Updated: Sep 22, 2025

Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

4.4K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.7K
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.7K

Area of Science:

  • Microbiology
  • Cardiovascular Science
  • Metabolic Science
  • Renal Science

Background:

  • Gut microbiota research has revealed its role in regulating cardiovascular, metabolic, and renal systems.
  • Chronic inflammation is a key factor in cardiometabolic disease, with microbial translocation contributing to this process.
  • Circulating microbiota, microbial communities in the bloodstream, are increasingly detected even in healthy individuals.

Purpose of the Study:

  • To review recent evidence on the characteristics and roles of circulating microbiota in cardiometabolic diseases.
  • To highlight emerging findings on circulating microbiota in patients with end-stage kidney disease undergoing hemodialysis.

Main Methods:

  • Review of current scientific literature on circulating microbiota and cardiometabolic diseases.
  • Analysis of recent advances in microbial DNA sequencing for identifying circulating microorganisms.
  • Focus on findings related to type 2 diabetes, cardiovascular disease, and chronic kidney disease.

Main Results:

  • Quantitative and compositional alterations in circulating microbiota are implicated in the pathogenesis of chronic inflammatory conditions.
  • Circulating microbiota may exert immunostimulatory, atherogenic, and cardiotoxic effects.
  • Emerging findings focus on circulating microbiota in end-stage kidney disease patients on hemodialysis.

Conclusions:

  • Circulating microbiota play a significant role in the development and progression of cardiometabolic diseases.
  • Further research into circulating microbiota is essential for understanding and managing these conditions.
  • Specific attention to circulating microbiota in patients with chronic kidney disease is warranted.