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Related Experiment Video

Updated: Sep 22, 2025

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release

Published on: June 12, 2021

Microbubbles Contrast Agents: General Overview as Diagnostics and Therapeutic Agent.

Shivani K Gharat¹, Shilpa C Godiyal¹, Pranali P Malusare¹

¹Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Navi Mumbai 400614, India.

Current Drug Targets

|May 20, 2022

Summary

Ultrasound-mediated microbubbles are powerful tools for drug delivery science. These contrast agents enable targeted delivery of various therapeutics, improving disease diagnosis and treatment.

Keywords:

Ultrasound contrast agents cavitation nuclei diagnostics microbubbles targeted delivery theranostic agents volumetric Oscillations

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Area of Science:

Drug delivery science
Biomedical engineering
Nanotechnology

Background:

Microbubbles are gas-filled spheres with a shell, used as contrast agents.
Their composition influences stability, efficiency, and clearance.
Ultrasound activation causes oscillations, enabling drug delivery applications.

Purpose of the Study:

To explore emerging applications of ultrasound-mediated microbubbles in drug delivery.
To highlight the potential of microbubbles for targeted therapeutic delivery.
To discuss their role in diagnosing and treating diseases.

Main Methods:

Utilizing microbubbles as ultrasound-activated agents.
Employing various drug loading techniques and targeting strategies.
Investigating diagnostic and therapeutic applications.

Main Results:

Microbubbles facilitate ultrasound-triggered drug delivery.
They enable targeted delivery of polynucleotides, proteins, genes, and small-molecule drugs.
Microbubbles show potential for disease diagnosis and treatment.

Conclusions:

Microbubbles are a versatile platform for advanced drug delivery.
Ultrasound-mediated microbubbles offer significant potential in medicine.
They aid in the accurate detection and treatment of diseases.