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Updated: Sep 22, 2025
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Origami with ABC Triblock Terpolymers Based on Glycopolymers: Creation of Virus-Like Morphologies
Aydan Dag1,2, Jiacheng Zhao1, Martina H Stenzel1
1Centre for Advanced Macromolecular Design, School of Chemistry and School of Chemical Engineering, The University of New South Wales, Sydney, NSW 2052, Australia.
Abstract:
Morphologies, that resemble viruses, were created using a single ABC triblock terpolymer poly(2-acryloylethyl-α-d-mannopyranoside)-b-poly(n-butyl acrylate)-b-poly(4-vinylpyridine) (PAcManA70-b-PBA369-b-PVP370). Morphologies ranging from flower-like micelles, cylindrical micelles, raspberry-like morphologies to nanocaterpillars were obtained by adjusting the pH value during the self-assembly process. The resulting nanoparticles had an abundance of mannose on the surface, which were recognized by the mannose receptors of RAW264.7, a macrophage cell line that can be used as a model for virus entry.
