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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Microbial Communities in Nature and Laboratory - Interview
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Earth Biogenome Project: present status and future plans.

Pushpendra Kumar Gupta1

  • 1Department of Genetics and Plant Breeding, Ch. Charan Singh University, Meerut, India 250004, India; Murdoch's Centre for Crop & Food Innovation, Murdoch University, Murdoch, WA 6150, Australia.

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Summary

The Earth Biogenome Project (EBP) aims to sequence the genomes of all known eukaryote species. This ambitious initiative is progressing through planned phases to achieve comprehensive genomic data for biodiversity research.

Keywords:
DNA sequencingbiodiversitygenomenetwork of networks

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Area of Science:

  • Genomics
  • Biodiversity Science
  • Eukaryotic Biology

Background:

  • The Earth Biogenome Project (EBP) is a global initiative launched in 2018.
  • It aims to generate high-quality reference genome sequences for all named extant eukaryote species.
  • The project is structured in phases, with a pilot phase (2018-2020) and Phase I (2020-2023) already underway.

Purpose of the Study:

  • To outline the current status and future trajectory of the Earth Biogenome Project.
  • To detail the sequencing goals for different project phases, covering approximately 1.8 million species.
  • To discuss the challenges inherent in sequencing a vast number of eukaryotic genomes.

Main Methods:

  • Genome sequencing of selected species during pilot and Phase I.
  • Phased approach for sequencing remaining species in Phases II (2024-2027) and III (2028-2030).
  • Leveraging scientific publications and special features (e.g., PNAS, January 2022) to disseminate progress.

Main Results:

  • Successful completion of the pilot phase and progress in Phase I, targeting 9400 species.
  • A clear roadmap established for sequencing the genomes of approximately 1.7 million additional species.
  • Growing scientific interest and engagement, as evidenced by coverage in prominent scientific journals.

Conclusions:

  • The EBP is making significant strides towards its goal of comprehensive eukaryotic genome sequencing.
  • The project's phased approach ensures systematic progress and data generation.
  • Addressing challenges will be crucial for the successful completion of this landmark biodiversity genomics effort.