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Cicatricial Conjunctivitis and Concurrent Clinical Features: A Case Study
Abdelsattar Farrag1, Anita Chan2,3,4, Louis Tong2,3,4
1Bolton NHS Foundation Trust, Farnworth, Bolton, UK.
Clinical Medicine Insights. Case Reports
|May 23, 2022
Summary
This case study highlights the management of cicatricial conjunctivitis, a condition causing chronic inflammation and fibrosis of the conjunctiva. Early diagnosis and treatment, including topical steroids and artificial tears, can improve patient symptoms.
Area of Science:
- Ophthalmology
- Immunology
Background:
- Cicatricial conjunctivitis presents with chronic inflammation and fibrosis.
- Distinguishing it from allergic conjunctivitis is crucial for effective management.
Observation:
- A 52-year-old man presented with bilateral red eyes, itching, symblepharon, and cicatrization.
- Examination revealed conjunctival hyperemia, Meibomian gland dysfunction, and superficial epitheliopathy.
- Conjunctival biopsy showed fibrosis and inflammation but no immune deposits.
Findings:
- Histopathology confirmed chronic stromal inflammation and fibrosis without mast cells, eosinophils, or immune deposits.
- The absence of immune deposits in the basement membrane aids in differential diagnosis.
Implications:
- This case illustrates the diagnostic challenges in cicatricial conjunctivitis.
- Appropriate management with topical corticosteroids and supportive care can lead to symptom improvement.
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