Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural history study of adults with primary central nervous system tumors: Initial results for first 1000 participants.

Neuro-oncology practice·2026
Same author

Factors Associated With Overall Survival and 90-Day Mortality Following Resection of Melanoma Brain Metastases.

Operative neurosurgery (Hagerstown, Md.)·2026
Same author

Intraoperative technological advances and new frontiers in precision glioma surgery.

Journal of neuro-oncology·2026
Same author

Pembrolizumab, Temozolomide and HSPPC-96 Vaccine in Newly Diagnosed Glioblastoma Post-Chemoradiation: Results from a Multi-institutional, Phase 2, Randomized, Placebo-Controlled Trial.

medRxiv : the preprint server for health sciences·2026
Same author

Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

Journal of neurosurgery·2026
Same author

Individualized multiparadigm mapping and standardized tablet-based task administration during awake craniotomy: associations with return to work and survival in diffuse gliomas.

Journal of neurosurgery·2026

Related Experiment Video

Updated: Sep 22, 2025

Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography
04:06

Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography

Published on: January 12, 2024

720

Assessing mobility in primary brain tumor patients: A descriptive feasibility study using two established mobility

James L Rogers1, Julianie De La Cruz Minyety1, Elizabeth Vera1

  • 1Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

Neuro-Oncology Practice
|May 23, 2022
PubMed
Summary

The Timed-Up-and-Go (TUG) and Five-Times Sit-to-Stand (TSS) tests are feasible for assessing mobility in primary brain tumor (PBT) patients. These tests can identify mobility impairments related to age, diagnosis, treatment, and symptom burden.

Keywords:
clinical cancer researchclinical observationsmobility assessmentsymptoms

More Related Videos

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

3.1K

Related Experiment Videos

Last Updated: Sep 22, 2025

Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography
04:06

Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography

Published on: January 12, 2024

720
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

3.1K

Area of Science:

  • Neuro-oncology
  • Clinical mobility assessment
  • Patient-reported outcomes

Background:

  • Primary brain tumors (PBT) significantly impact patient mobility.
  • Objective mobility assessment is crucial for PBT patient care.
  • Established mobility tests may offer utility in neuro-oncology settings.

Purpose of the Study:

  • To evaluate the preliminary utility and feasibility of the Timed-Up-and-Go (TUG) and Five-Times Sit-to-Stand (TSS) tests.
  • To assess mobility status in primary brain tumor (PBT) patients.
  • To identify factors associated with mobility impairment in PBT patients.

Main Methods:

  • Adult PBT patients completed TUG/TSS tests and the MD Anderson Symptom Inventory-Brain Tumor module (MDASI-BT).
  • Feasibility metrics (completion times/rates) and patient data were collected.
  • Statistical analyses (Mann-Whitney, Kruskal-Wallis, Spearman's rho) examined test completion times and patient characteristics.

Main Results:

  • The TUG/TSS tests were completed by 94% of the 66 PBT patients.
  • Older age, new diagnosis, corticosteroid use, and poor Karnofsky Performance Status (KPS) were linked to longer TUG/TSS completion times.
  • Increased activity-related symptom interference correlated with longer TUG/TSS test completion times.

Conclusions:

  • The TUG/TSS tests demonstrate feasibility and potential clinical utility for PBT patients.
  • These tests can help identify mobility impairments associated with various clinical factors.
  • Further research is needed to explore longitudinal feasibility and utility in diverse settings.