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Updated: Sep 22, 2025

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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Kicking KRAS to tackle lung cancer
1Communications Medicine, https://www.nature.com/commsmed.
Communications Medicine
|May 23, 2022
Abstract:
KRAS is one of the most commonly mutated oncogenes in lung cancer but has long been considered undruggable. With the recent FDA approval of sotorasib, supported by positive phase II trial data now published in The New England Journal of Medicine, this is no longer the case.
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